C/EBPβ/AEP pathway dictates both Alzheimer’s disease and longevity: Study

March 31, 2022

Cognitive decline during normal aging is exacerbated in neurodegenerative disease including Alzheimer’s disease (AD). While it is not yet known exactly what causes AD, there are a number of risk factors that make a person more likely to get it. Among them, aging is the most prominent one.

Researchers find contaminated water in fast-food soda fountains
Loma Linda University (LLU) researchers found microbial contamination in common sources of drinking water in the Eastern Coachella Valley, including soda fountains at fast-food restaurants. Their findings revealed that 41% of the water samples researchers collected from these soda fountains contained total coliforms, an indicator of water contamination.
Combination radiation with immunotherapy shows promise against 'cold' breast cancer tumors
Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy—one that boosts T cells, and another that boosts dendritic cells—can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone. Immunotherapy activates the body's own immune system to fight cancer but isn't effective for difficult-to-treat "cold" tumors, like this.
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Autistic individuals have increased risk of chronic physical health conditions across the whole body
Autistic people have higher rates of chronic physical health conditions across the whole body and are more likely to have complex health needs, according to a study led by researchers at the University of Cambridge. Their findings, published in the journal Molecular Autism, have important implications for the clinical care of autistic people.
Team presents new approach to discover targets for Alzheimer's, other diseases with protein phase separation
Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions. Protein phase separation at the wrong place or time could create clogs or aggregates of molecules linked to neurodegenerative diseases like Alzheimer's and Parkinson's, and poorly formed cellular condensates could contribute to cancers and might help explain the aging process.

C/EBPβ/AEP pathway dictates both Alzheimer’s disease and longevity: Study

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