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Neuroscientists create new resource to improve Alzheimer’s disease research models

A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain—a known sign of Alzheimer’s disease and several other neurodegenerative diseases. The study’s findings, recently published in the Journal of Experimental Medicine, could lead to better research models that improve understanding of how different genetic backgrounds influence neurodegenerative disease development and treatment needs.