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Novel positron emission tomography tracer visualizes synucleinopathies

Brain imaging scans are powerful tools for diagnosing Parkinson’s disease (PD) and ruling out other motor disorders. In PD, the presence of α-synuclein (α-Syn) in Lewy bodies and Lewy neurites in the brain, particularly the substantia nigra, distinguishes it from other parkinsonisms. Unfortunately, there is currently no effective α-Syn PET tracer available.