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Potential Alzheimer’s treatment would use high-frequency terahertz radiation

Amyloid deposition is a hallmark of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). The deposition process is described as a sigmoidal curve in which the misfolded proteins assemble into oligomers before fibril elongation. This dynamic process is accompanied by the misfolded monomer with more α-helix formed into abundant crosslinked β-sheet structure. Targeting the toxic accumulation may represent a promising strategy to slow or prevent disease initiation.