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Protein changes in cerebrospinal fluid indicate inflammatory processes in the brain

Alzheimer’s, Parkinson’s and other neurodegenerative diseases are associated with inflammatory processes in the brain. German researchers have succeeded in identifying a group of proteins in cerebrospinal fluid that could provide information about such inflammatory processes. As so-called biomarkers, the proteins could help researchers to better understand disease processes in the future and to test the effect of potential drugs against brain inflammation. The research team led by Stephan Käser and Professor Dr. Mathias Jucker at the Hertie Institute for Clinical Brain Research and the University of Tübingen, in collaboration with Professor Dr. Stefan Lichtenthaler from the Munich site of the German Center for Neurodegenerative Diseases, has now published its study in the journal PNAS.