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Researchers investigate inhibitory mechanism in Alzheimer’s disease

Alzheimer’s disease (AD) is a form of progressive dementia interfering with daily living. It is caused by the decline in the number of brain cells resulting in the deterioration of our mental abilities. One of the main reasons for the worsening brain cells condition and even the brain shrinkage are molecules having a specific structure called β-amyloids (Aβ). They are peptides that tend to agglomerate around the nerve cells, becoming toxic and damage them. Recent studies, presented by scientists from the Institute of Physical Chemistry, Polish Academy of Sciences, led by dr. Piotr Pieta, give hope for inhibition of the β-amyloids’ toxicity by applying the K162 molecule. Researchers present a tremendous protective impact on the biological membranes and explain its inhibition mechanism.