The causes of Alzheimer’s disease (AD) are unclear, and the interventions for AD are very limited. However, researchers led by Prof. He Zhuohao from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, in collaboration with researchers worldwide, have recently proposed a new strategy for the intervention in certain neurodegenerative diseases, including AD, based on a better understanding of disease mechanisms. Their study was published in Science Translational Medicine.