Alzheimer’s disease research in brain tissue from African American donors points to roles for many novel genes

October 8, 2025

The prevalence of Alzheimer’s disease (AD) is approximately two times higher in African Americans (AA) compared to white/European-ancestry (EA) individuals living in the U.S. Some of this is due to social determinants of health such as disparities in health care access and quality of education, biases in testing and higher rates of AD risk factors such as cardiovascular disease and diabetes in those who identify as African American.

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Alzheimer’s disease research in brain tissue from African American donors points to roles for many novel genes

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