To help neurologists, patients and their families understand the current evidence on the use of aducanumab to treat Alzheimer’s disease, the American Academy of Neurology (AAN) has issued an evidence-in-focus article, published in the February 23, 2022, online issue of Neurology, the medical journal of the AAN. The article also includes a discussion of the safety, costs, administration, and quality-of-life issues related to aducanumab to provide people with a more detailed understanding of the new treatment.