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Drug that slows progression of ALS may provide the same benefit for people with Alzheimer’s disease

Riluzole, a drug that has been used for more than 20 years to slow the progression of ALS, commonly known as Lou Gehrig’s disease, was shown in a pilot phase 2 study to slow brain metabolic decline and have a positive effect on cognitive performance versus placebo in people with mild Alzheimer’s disease. The study was pre-published in a recent online issue of the journal Brain. The Alzheimer’s Drug Discovery Foundation (ADDF) provided funding and expertise to study investigators, helping to bring this research into phase 2 clinical testing.