Has a treatment for Alzheimer’s been sitting on pharmacy shelves for decades? Scientists have two possible candidates

November 1, 2021

Two drugs approved decades ago not only counteract brain damage caused by Alzheimer’s disease in animal models, the same therapeutic combination may also improve cognition.

Study reports discovery of new cell type in thymus
It came as a surprise to Professor David Lo and his graduate student Diana Del Castillo when they were recently consulted by researchers in Israel for their expertise on specialized cells called Microfold cells, or M cells, which are mostly known for their presence in the intestinal epithelium. The Israeli group had identified similar cells in the thymus, an organ located just above the heart that makes lymphocytes—white blood cells that play an important role in the immune system and protect the body against infection.
Researchers uncover new genetic traits influencing Alzheimer's risk
Researchers at the University of Pittsburgh analyzed thousands of human genomes to find new gene variations responsible for controlling the levels of blood plasma molecules linked to Alzheimer's disease risk. The findings, published recently in Molecular Psychiatry, could contribute to the future development of simple blood tests for the disease.
New study: Reversing aging in the blood stem cells and the immune system
As we age, our bodies face numerous challenges, including a decline in immune system function and an increased vulnerability to various health issues. An innovative study has recently shed light on these challenges and unveiled a potential solution that could have far-reaching implications for aging individuals.
Investigators devise test to identify brain tumors from cerebrospinal fluid
Researchers with the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine and four other institutions have developed a molecular test to identify the presence of brain tumors by measuring abnormal genetic material shed by tumors and circulating in cerebrospinal fluid (CSF). A description of the work was published in the journal Cell Reports Medicine.
Empowering Europe against infectious diseases: An innovative framework to tackle climate-driven health risks
Climate change is one of several drivers of recurrent outbreaks and geographical range expansion of infectious diseases in Europe.

Has a treatment for Alzheimer’s been sitting on pharmacy shelves for decades? Scientists have two possible candidates

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