Lowering a form of brain cholesterol reduces Alzheimer’s-like damage in mice

November 22, 2023

In Alzheimer’s disease and related dementias, cognitive decline is driven by the over-accumulation of a normal brain protein known as tau. Wherever tau builds up, nearby brain tissue starts to degenerate and die.

North Carolina is distributing Benadryl and EpiPens as yellow jackets swarm from Helene flooding
Deadly flooding from Hurricane Helene in western North Carolina has also disrupted the underground nests of yellow jackets, bees and other insects, causing them to swarm and sting people struggling to recover from the storm.
Use of the term 'postcode lottery' and its meaning has changed dramatically over time, UK study shows
New research shows the idea of the "postcode lottery" was first used in 1997 to express concern about how access to National Health Service (NHS) drugs and treatment varied from place to place. But its meaning has since broadened to include regional inequalities in state services generally, and even in poverty and life expectancy.
Brain molecule reverses movement deficits of Parkinson's, offering new therapeutic target
A research team from the University of California, Irvine is the first to reveal that a molecule in the brain—ophthalmic acid—unexpectedly acts like a neurotransmitter similar to dopamine in regulating motor function, offering a new therapeutic target for Parkinson's and other movement diseases.
Regular light-intensity exercise can help erase fear memories and prevent PTSD, study suggests
Post-traumatic stress disorder (PTSD) is a common mental disorder caused by severe stress. Recent research suggests that exercise can help prevent and treat PTSD. However, the specific effects of light-intensity exercise (LIE) on PTSD symptoms remain unclear.
A multicomponent program for promoting physical activity among remote workers in Japan
The shift to remote work during the COVID-19 pandemic has adversely affected the physical activity levels of office and desk workers. Previous studies have shown that remote workers are generally less active and more sedentary than office workers, which increases their health risks. However, researchers noted that few countermeasures exist for promoting physical activity among remote workers.

Lowering a form of brain cholesterol reduces Alzheimer’s-like damage in mice

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