Mitochondrial dysfunction linked to Alzheimer’s onset and treatment response

August 7, 2025

Changes in how brain cells generate energy may drive the development of Alzheimer’s disease and influence how patients respond to therapy, according to a new study from Mayo Clinic researchers. The findings, published in the journal Alzheimer’s & Dementia, spotlight mitochondrial complex I—a critical component of cellular energy production—as both a contributor to disease progression and a promising target for new treatments.

Autistic children born preterm often show more complex needs—but share similar genetic background
A new study shows that children born preterm who are later diagnosed with autism often present with more extensive support needs and a higher number of co-occurring conditions than autistic children born at full term. Surprisingly, however, the researchers found no differences in genetic variants across the genome, nor in specific genes already linked to autism, between the groups—a result that contradicted their initial hypothesis.
Shredded cheese recalled over possible metal fragments, FDA says
A large recall of shredded cheese sold under several popular grocery store brands is now underway after the manufacturer reported the product may contain small metal fragments, according to the U.S. Food and Drug Administration (FDA).
Antibody halts triple-negative breast cancer in preclinical models
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies. Even when patients initially respond to treatment, the cancer often returns and is more resistant than before.
Planned birth at term reduces pre-eclampsia in those at high risk, clinical trial finds
Planned birth at term reduces the incidence of preeclampsia in women at high risk of the condition, without increasing emergency Cesarean or neonatal unit admission, according to new trial results.
AI method recovers missing movement data to enhance behavioral analysis
Scientists learn about the brain's inner workings by studying what animals or people do, how they move, react, and make choices. Behavior is complex, as animals and humans can move in countless different manners. Yet, neuroscience studies have heavily relied on constrained, simplistic behaviors, which are easier to analyze and quantify.

Mitochondrial dysfunction linked to Alzheimer’s onset and treatment response

Recent Posts

JUST IN