Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

March 25, 2025

A new open-source model of brain metabolism—the most complex ever generated—has shown how altering key chemicals could restore aged cells to their youthful activity and resilience.

New study on darbepoetin shows how to best reduce need for blood transfusions in premature babies
A new study published in the Journal of Perinatology is helping premature babies avoid blood transfusions, thanks to new research and collaboration between researchers at Intermountain Health in Salt Lake City and the University of Utah.
Trial of structural heart interventions shows promising results
Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure used to replace damaged heart valves, offering patients an alternative to open heart surgery. Over the last decade, there has been a dramatic shift in the treatment of valvular heart disease, and today, the majority of patients with aortic stenosis who undergo aortic valve replacement have a TAVR procedure.
Updated equestrian helmet ratings system adds racing and high-speed events
Falling off a horse at high-speed changes the impact to the rider's head and the parameters for a quality helmet, according to new research from the Virginia Tech Helmet Lab.
Cancer research in the US is world class. With the government pulling out, its future is uncertain
Cancer research in the U.S. doesn't rely on a single institution or funding stream − it's a complex ecosystem made up of interdependent parts: academia, pharmaceutical companies, biotechnology startups, federal agencies and private foundations. As a cancer biologist who has worked in each of these sectors over the past three decades, I've seen firsthand how each piece supports the others.
Study using simulations highlights power of pooled data in environmental health research
Conflicting findings in environmental epidemiology have long stalled consensus on the health effects of toxic chemicals. A new study by Columbia University Mailman School of Public Health published in the American Journal of Epidemiology suggests that one major reason for these inconsistencies may be the limited exposure ranges in individual studies—leading to underpowered results and unclear conclusions.

Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments

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