Mutant gene stops at-risk people from getting Alzheimer’s: Could it lead to treatment? June 1, 2022 The APOE4 gene is the most powerful genetic factor driving a person’s risk for developing late-onset Alzheimer’s disease. Post navigation Previous Previous post: Investigating the links between facial recognition and Alzheimer’s diseaseNext Next post: Toxic protein ‘variant’ may be the next target for ALS therapies