New mouse model mimics earliest stages of Alzheimer’s disease

December 1, 2021

Drug hunters hoping to prevent or delay the onset of Alzheimer’s disease take note—a new mouse model developed at RIKEN offers a powerful platform for evaluating potential therapies designed to combat the neurodegenerative disease in its earliest stages.

Precarious employment conditions can increase risk of early death
People without a secure job contract can reduce their risk of premature death by 20 percent if they gain permanent employment, a study from Karolinska Institutet published in the Journal of Epidemiology and Community Health reports. According to the researchers, the results indicate that job security on the Swedish labor market needs to improve.
Network-based approaches open a new avenue to classify and treat rare diseases
Network-based approaches often unveil what remains concealed—this holds true in medical research as well. For several years, CeMM Adjunct Principal Investigators Kaan Boztug, Director of St. Anna Children's Cancer Research Institute, and Jörg Menche, a professor at the University of Vienna and Max Perutz Labs have been working to gain a better systemic and molecular understanding of rare diseases, congenital immune disorders, and congenital inflammatory disorders by using network-based methods.
Immune cells shape their own path: Scientists show how immune cells migrate along self-generated gradients
When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) have now discovered that immune cells actively generate their own guidance system to navigate through complex environments. This challenges earlier notions about these movements.
Empowering personalized care: Cancer treatment to benefit from AI-driven imaging platform
SFU engineering science professor Mirza Faisal Beg is spearheading research that could help to redefine cancer treatment. Using artificial intelligence (AI) his breakthrough research enables imaging of the human body and organ measurements much faster than traditional methods, signaling a leap forward in harnessing AI for individually personalized health care solutions.
Taking the guess work out of spinal surgery
Spinal fusion is a highly invasive surgery where an implant is placed in the spine to prevent movement between bones. The treatment has a high failure rate after only five years, however Te Whare Wānanga o Waitahi | University of Canterbury researcher and lecturer Associate Professor Debbie Munro has spent the last 20 years finding a way to change this.

New mouse model mimics earliest stages of Alzheimer’s disease

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