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New signaling pathway in neurons

Neurodegenerative diseases, such as various forms of senile dementia or amyotrophic lateral sclerosis (ALS), have one thing in common: large amounts of certain RNA-protein complexes (snRNPs) are produced and deposited in the nerve cells of those affected—and this hinders the function of the cells. The overproduction is possibly caused by a malfunction in the assembly of the protein complexes.