Next-generation tau radiotracers outperform FDA-approved imaging agents in detecting Alzheimer’s disease

January 30, 2025

Two new PET radiotracers have outperformed the only current Food and Drug Administration (FDA) approved radiotracer for detecting tau tangles in the brain, a hallmark of Alzheimer’s disease. In a head-to-head comparison of the three imaging agents, the next-generation radiotracers exhibited higher binding to Alzheimer’s disease brain tissue and a greater selectivity for identifying the tangles. This research, which was published in the January issue of The Journal of Nuclear Medicine, could play a key role in measuring outcomes of clinical trials for Alzheimer’s disease treatments.

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Next-generation tau radiotracers outperform FDA-approved imaging agents in detecting Alzheimer’s disease

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