Phosphodiesterase-5 inhibitors not tied to alzheimer disease risk

October 19, 2022

Phosphodiesterase-5 (PDE5) inhibitors seem not to be associated with a reduced risk for Alzheimer disease and related dementia, according to a study published online Oct. 4 in Brain Communications.

Hormone supplementation in rhesus monkeys points to potential autism treatment
For years, Florida Tech's Catherine Talbot, an assistant professor of psychology, has worked to understand the sociality of male rhesus monkeys and how low-social monkeys can serve as a model for humans with autism. Her most recent findings show that replenishing a deficient hormone, vasopressin, helped the monkeys become more social without increasing their aggression—a discovery that could change autism treatment.
Researchers find link between HPV and thyroid eye disease
University of Miami Miller School of Medicine researchers have identified molecular evidence linking human papillomavirus (HPV) to thyroid eye disease (TED) through molecular mimicry involving HPV capsid proteins and autoimmune targets. Elevated antibody levels against HPV appeared in participants with TED, suggesting a possible immunological connection influencing disease development.
Traffic-related ultrafine particles found to influence gene regulation in olfactory cells
Exposure to air pollution–derived ultrafine particles alters gene transcription by epigenetic mechanisms, a new study shows. The changes affected, for example, cellular survival.
Exercise may yield improved sleep quality in women with PTSD symptoms
High-intensity exercise can improve sleep quality—possibly by reducing anxiety and hyperarousal symptoms—in women with post-traumatic stress disorder (PTSD) symptoms, according to new research from the University of Georgia's Department of Kinesiology.
Dopamine signals when a fear can be forgotten, study shows
Dangers come but dangers also go and when they do, the brain has an "all-clear" signal that teaches it to extinguish its fear.

Phosphodiesterase-5 inhibitors not tied to alzheimer disease risk

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