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Proteomic profile study reveals signatures for distinguishing different forms of Alzheimer’s disease

Researchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzheimer’s disease (AD). In a paper, “Proteomics of brain, CSF, and blood identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease,” published in Science Translational Medicine, the researchers identify specific and shared proteomic changes associated with sporadic Alzheimer’s disease (AD) across brain tissue, cerebrospinal fluid (CSF), and blood.