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Uncovering the molecular mechanism behind synapse loss in Alzheimer’s disease

Korea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Circuits Research Group have identified the mechanism causing synaptic loss in Alzheimer’s disease as the aberrant expression of RAPGEF2, a synaptic protein.