New insights into the pathogenesis of Alzheimer’s disease could unlock novel therapeutic approaches and help to prevent the disease. A study led by Professors Marcus Grimm and Tobias Hartmann at the Rhineland Campus of the SRH University of Applied Health Sciences in Leverkusen and at Saarland University has shed light on a bidirectional interaction in the body’s fat metabolism that could play an important role in the development of the disease. Dietary and other lifestyle factors such as smoking also play a role.